Most pediatric tumors are "small round blue cell tumors." The histology slide above shows sheets of small, blue cells from Ewing sarcoma.
Pathology for these tumors shows small round cells that stain with blue on routine H&E stained sections
"Small round blue cell tumors" include childhood cancers such as:
- Ewing sarcoma
- Desmoplastic small round blue cell tumor
Under the microscope all the different types of small round blue cell tumors look very similar.
Different methods have been developed to distinguish these tumors:
- Immunohistochemistry (special stains)
- Molecular studies and Cytogenetics
- Electron microscopy
Here are the descriptions of some different examples of this tumor type: