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Hodgkin Lymphoma

 

 

Other Organ Involvement

 

 

Summary of Different Organ involvement in Hodgkin Lymphoma:

Region

Type of involvement

Lungs

(15 - 20% of cases)

Four types of involvement:

  • Contiguous with nodal disease
  • Peribronchovascular disease
  • Subpleural - plaque like pleural involvement
  • Parenchymal - nodular and alveolar

 

Bone Marrow

(5% of all cases)

  • Tends to involve bone marrow focally

Bone

(2% of all cases)

  • Lytic, destructive bone lesion - unusual

Liver

(1 - 2% of all cases)

  • Spleen is also usually involved

 

  • Jaundice is usually due to advanced disease
  • Parenchymal disease
  • Obstruction at porta hepatis by lymph node mass

 

CNS Paraneoplastic syndromes

(less than I% of cases)

  • Due to autoimmune disorders associated with Hodgkin Lymphoma

Skin

(less than 1% of cases)

  • Skin nodules and involvement rare and only seen in advanced disease

 

  • Paraneoplastic skin rashes (autoimmune disorder) can occur - urticaria and bullous rashes

 

 

 

 

 

 

 

 

 

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