Systemic
B-symptoms:
Specific systemic symptoms with important prognostic significance.
Seen in ~one third of cases
- Fever > 38.0 degrees C
- Weight loss (>10% of baseline body weight over past 6 months)
- Drenching Night sweats
Other systemic symptoms may include:
- Pel-Ebstein Fever (waxing-and-waning course over days to weeks)
- Anemia or Weakness from Bone Marrow Involvement
- Pruritis (itching)
- seen in 15-25%
- usually mild usually associated with advanced disease
- commoner in women
- generalized
- usually resolves when Hodgkin lymphoma is treated
- was previously characterized as a “B-symptom” but not found to have prognostic significance
- Alcohol-induced pain at site of involved LNs
