The differential diagnosis of Wilms tumor includes benign processes as well as malignancies.
Neuroblastoma is the most common differential diagnosis of Wilms tumor.
Features that distinguish between Wilms tumor and Neuroblastoma:
Wilms Tumor |
Neuroblastoma |
|
Abdominal mass |
Yes |
Yes |
Primary origin |
Intrarenal |
Extrarenal |
Physical examination |
Displacing mass, mainly confined to the flank |
Non-mobile mass. more likely to cross the midline |
Pattern of tumor spread |
Direct expansion with displacement of adjacent structures |
Encasement of vessels and aortic elevation |
Other |
Intrinsically displaces urinary collecting systems |
Externally displaces kidney Often calcified |
- In addition to neuroblastoma, other neoplasms are sometimes confused with Wilms tumor based on similar clinical presentations.
- There are benign and malignant causes of an abdominal mass.
Differential diagnoses of a Renal Mass:
Benign |
Malignant |
Multicystic kidneys |
Fibrosarcoma |
