Why Bone Marrow Transplants are done:
Hematopoietic Stem Cell Transplant = HSCT - (also known as a Blood and Marrow
Transplant or BMT) serves many purposes including:
- Curative therapy for malignant diseases (e.g. ALL, AML)
- Replacement of:
- A dysfunctional immune system with a new immune system (e.g. Severe Combined Immunodeficiency Syndromes)
- Single enzymes that are genetically missing (e.g. Hurler Syndrome)
- One’s own hematopoietic stem cells following myeloablative chemotherapy (e.g. autologous transplant for solid tumors)
- Abnormal red blood cells with normal red blood cells (e.g. Beta Thalassemia).
- Entire hematopoietic system in marrow failure syndromes (e.g. Severe Aplastic Anemia).
