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Osteogenic Sarcoma

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Chemotherapy related long-term complications in Osteogenic sarcoma:

Chemotherapy Agent	Long Term Effect
Adriamycin	Cardiomyopathy Dose dependent
Bleomycin	Pneumonitis and interstitial lung disease
Etoposide	Secondary AML (short latent period)
Cisplatin	Hearing loss Renal dysfunction
Alkylating agent cyclophosphamide	Secondary AML
	Hemorrhagic cystitis with long-term increased risk of bladder cancer
	Infertility

Acknowledgements:

Editor in Chief
Dr. Karen Goddard

Web site Manager
Danielle Lawless

Major Contributors:

Dr. Mason Bond

Dr. Paul Clarkson

Dr. Thomas Hess
Vivian Ma

Contributors:
Dr. Karen Goddard
Dr. Daniel Levine

Dr. Deborah McFadden
Dr. Torsten Nielsen
Dr. Malcolm Hayes

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