The treatment of Ewing sarcoma (ES) requires a combined modality approach.
Therapy must be multidisciplinary with a team of surgical, medical and radiation oncologists.
Chemotherapy is critical to have any hope of achieving local or distant control.
Local control also requires:
- Surgery
- Radiation therapy (RT)
- Combination of both surgery and RT.
Multidrug chemotherapy for ES includes:
- Vincristine
- Doxorubicin
- Ifosfamide
- Etoposide
- Cyclophosphamide is included in most protocols
- Method of administration and dose intensity within courses differs between protocols
- Dactinomycin included in some protocols
External Link:
Ewing treatment option overview at the National Cancer Institute
